Publications

Schnepf D, Crotta S, Thamamongood T, Stanifer M, Polcik L, Ohnemus A, Vier J, Jakob C, Llorian M, Gad HH, Hartmann R, Strobl B, Kirschnek S, Boulant S, Schwemmle M, Wack A, Staeheli P. 2021. Selective Janus kinase inhibition preserves interferon-λ-mediated antiviral responses. Sci Immunol. 6(59):eabd5318. doi: 10.1126/sciimmunol.abd5318.

Català-Moll F, Ferreté-Bonastre AG, Li T, Weichenhan D, Lutsik P, Ciudad L, Álvarez-Prado ÁF, Rodríguez-Ubreva J, Klemann C, Speckmann C, Vilas-Zornoza A, Abolhassani H, Martínez-Gallo M, Dieli-Crimi R, Rivière JG, Martín-Nalda A, Colobran R, Soler-Palacín P, Kracker S, Hammarström L, Prosper F, Durandy A, Grimbacher B, Plass C, Ballestar E. 2021. Activation-induced deaminase is critical for the establishment of DNA methylation patterns prior to the germinal center reaction. Nucleic Acids Res. 49(9):5057-5073.

Emmerich F, Zschiedrich S, Reichenbach-Braun C, Süsal C, Minguet S, Pauly MC, Seidl M.2021. Low Pre-Transplant Caveolin-1 Serum Concentrations Are Associated with Acute Cellular Tubulointerstitial Rejection in Kidney Transplantation. Molecules. 26(9):2648.

Fliegauf M, Krüger R, Steiner S, Hanitsch LG, Büchel S, Wahn V, von Bernuth H, Grimbacher B. 2021. A Pathogenic Missense Variant in NFKB1 Causes Common Variable Immunodeficiency Due to Detrimental Protein Damage. Front Immunol. 12:621503.

Hatscher L, Lehmann CHK, Purbojo A, Onderka C, Liang C, Hartmann A, Cesnjevar R, Bruns H, Gross O, Nimmerjahn F, Ivanović-Burmazović I, Kunz M, Heger L, Dudziak D. 2021. Select hyperactivating NLRP3 ligands enhance the TH1- and TH17-inducing potential of human type 2 conventional dendritic cells. Sci Signal. 14(680):eabe1757.

Mertens, J., J. R. Herdy, L. Traxler, S. T. Schafer, J. C. M. Schlachetzki, L. Bohnke, D. A. Reid, H. Lee, D. Zangwill, D. P. Fernandes, R. K. Agarwal, R. Lucciola, L. Zhou-Yang, L. Karbacher, F. Edenhofer, S. Stern, S. Horvath, A. C. M. Paquola, C. K. Glass, S. H. Yuan, M. Ku, A. Szucs, L. S. B. Goldstein, D. Galasko, and F. H. Gage. 2021. Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients. Cell Stem Cell. S1934-5909(21)00161-2.

Micheau O, Rizzi M, Smulski CR. 2021. Editorial: TNFR Superfamily Oligomerization and Signaling. Front Cell Dev Biol. 9:682472.

Gámez-Díaz L, Grimbacher B. 2021. Immune checkpoint deficiencies and autoimmune lymphoproliferative syndromes. Biomed J. 19:S2319-4170(21)00038-X. doi: 10.1016/j.bj.2021.04.005.

Neuwirt E, Gorka O, Saller BS, Groß CJ, Madl T, Groß O. 2021. NLRP3 as a sensor of metabolism gone awry. Curr Opin Biotechnol. 68:300-309.

Hartl, F. A., J. Ngoenkam, E. Beck-Garcia, L. Cerqueira, P. Wipa, P. Paensuwan, P. Suriyaphol, P. Mishra, B. Schraven, S. Gunther, S. Pongcharoen, W. W. A. Schamel, and S. Minguet. 2021. Cooperative Interaction of Nck and Lck Orchestrates Optimal TCR Signaling. Cells 10(4):834.

Wang, L., D. Aschenbrenner, Z. Zeng, X. Cao, D. Mayr, M. Mehta, M. Capitani, N. Warner, J. Pan, L. Wang, Q. Li, T. Zuo, S. Cohen-Kedar, J. Lu, R. C. Ardy, D. J. Mulder, D. Dissanayake, K. Peng, Z. Huang, X. Li, Y. Wang, X. Wang, S. Li, S. Bullers, A. N. Gammage, K. Warnatz, A. I. Schiefer, G. Krivan, V. Goda, W. H. A. Kahr, M. Lemaire, C. Genomics England Research, C. Y. Lu, I. Siddiqui, M. G. Surette, D. Kotlarz, K. R. Engelhardt, H. R. Griffin, R. Rottapel, H. Decaluwe, R. M. Laxer, M. Proietti, S. Hambleton, S. Elcombe, C. H. Guo, B. Grimbacher, I. Dotan, S. C. Ng, S. A. Freeman, S. B. Snapper, C. Klein, K. Boztug, Y. Huang, D. Li, H. H. Uhlig, and A. M. Muise. 2021. Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice. Nat Genet 53: 500-510.

Nauroy, P., and D. Kiritsi. 2021. Research in practice: Towards deciphering the role of epidermal proteases in recessive dystrophic epidermolysis bullosa progression. J Dtsch Dermatol Ges. doi: 10.1111/ddg.14396.

Emig, R., W. Knodt, M. J. Krussig, C. M. Zgierski-Johnston, O. Gorka, O. Gross, P. Kohl, U. Ravens, and R. Peyronnet. 2021. Piezo1 Channels Contribute to the Regulation of Human Atrial Fibroblast Mechanical Properties and Matrix Stiffness Sensing. Cells 10: 663.

Globig, A. M., M. Heeg, C. S. Larsen, R. D. Ferreira, G. Kindle, S. Goldacker, V. Strohmeier, S. L. Silva, C. Cunningham-Rundles, I. Quinti, R. Thimme, D. Bettinger, M. Schultheiss, and K. Warnatz. 2021. International multicenter experience of transjugular intrahepatic portosystemic shunt implantation in patients with common variable immunodeficiency. J Allergy Clin Immunol Pract. 13:S2213-2198(21)00301-9.

Ehl, S., T. von Bahr Greenwood, E. Bergsten, A. Fischer, J. I. Henter, M. Hines, K. Lehmberg, G. Janka, D. Moshous, and K. E. Nichols. Is neutralization of IFN-gamma sufficient to control inflammation in HLH? Pediatr Blood Cancer 68: e28886.

Kohler, N., D. A. Ruess, R. Kesselring, and R. Zeiser. 2021. The Role of Immune Checkpoint Molecules for Relapse After Allogeneic Hematopoietic Cell Transplantation. Front Immunol 12: 634435.