Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells

January 12, 2024 11:48 am Published by

Baik R, Cromer MK, Glenn SE, Vakulskas CA, Chmielewski KO, Dudek AM, Feist WN, Klermund J, Shipp S, Cathomen T, Dever DP, Porteus MH. 2024. Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells. Nat Commun. 2024 Jan 2;15(1):111. doi: 10.1038/s41467-023-43413-w.

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This post was written by Heike Ufheil