The research group of Dr. Katrin Kierdorf (C05N) is mainly interested to understand the homeostatic function and maintenance of tissue macrophage networks and is investigating the underlying processes and mechanisms. Tissue macrophages are resident immune cells and found in nearly every tissue from insects to mammals. Whereas tissue macrophages are well known to fight back infections and repair tissues, they also serve a plethora of physiological functions under steady state conditions to maintain tissue homeostasis. Our research group is mainly interested to understand the molecular machineries guiding unique macrophage networks are created in each organ and how these cells communicate throughout their network during homeostasis and disturbance. We are looking for a motivated PhD candidate, who is willing to embark on our journey to explore how macrophages define their cell number in defined tissue niches and how alterations in network assembly can lead to immune-mediated pathologies. Here we will employ two model systems, the mouse and the fruit fly, with a wide range of different techniques including flow cytometry, transcriptomics, metabolomics, histology, automated image analysis or in vivo imaging.
We are looking for a highly motivated and ambitious candidate with a strong interest in immunology and a huge commitment to scientific research. The candidate should hold a master’s degree in biology, biomedicine or an equivalent discipline. Experience in immunological methods or work with flies or mice is desirable.
We are offering a PhD position (E13 65%) within a young, international and motivated group of researchers aiming to decipher macrophage development and biology. We are well embedded in the excellent immunological research environment in Freiburg. The position is initially available for three years and should be filled as soon as possible.
You are interested to apply? Interested candidates should send a CV, a strong motivation letter and at least two reference letters to Dr. Katrin Kierdorf (katrin.kierdorf@uniklinik-freiburg.de) .