The Collaborative Research Center (CRC) 1160. “Immune-mediated pathology as a consequence of impaired immune reactions (IMPATH)” is a research consortium of clinical and basic immunologists exploring the basis of diseases mediated by the immune system.
The CRC sets out to challenge the traditional idea that an “overreaction” or “deviation“ of normal immune responses is pivotal to immune mediated pathology and that, consequently, immunosuppression is the appropriate therapeutic strategy for such disorders. Instead, the conceptual basis of the CRC is the idea that impaired immune reactions constitute a major prerequisite for immunopathology. This is what we call the “IMPATH paradox”. This paradox implies that immune reconstitution and/or immune stimulation rather than immunosuppression represent appropriate therapeutic principles for these forms of immunopathology.
On behalf of the boards of the CRC 1160 – IMPATH and the Center for Chronic Immunodeficiency (CCI), we are delighted to invite you to participate to the “From Paradigms to Paradoxes in Immunity and Immunopathology (PPII) International Conference” – to be held in Freiburg from 06-08 October 2022.
The Upper Rhine Immunology (URI) meeting will bring together researchers from Strasbourg, Basel, Karlsruhe and Freiburg who will present their recent work and expert views in the fields of adaptive and innate immunity, signaling and immune response, hematopoiesis, immunodeficiency, inflammation and disease, as well as immunotherapy.
The prize that was awarded for the first time 2021, goes to PD Dr. Susana Minguet (B01) for the molecular control of the T cell response enabling an improved CAR-T-cell therapy. Congratulations!
We are happy to announce the Klaus Goettler Awardee Ms. Janine Kemming (A06). Congratulations!
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