Publications

Wenger V, Garcia-Manero G, Zeiser R, Lübbert M. 2026. DNA methyltransferase inhibitors in hematological malignancies and solid tumors. Int J Cancer. 158(2):433-461. doi: 10.1002/ijc.70197.

Fliegauf M, Nitschke K, Mrovecova P, Posadas-Cantera S, Camacho-Ordonez N, Warnatz K, Keller B, Grimbacher B. Compound heterozygous NFKB1 missense variants in cis associated with immunodeficiency. 2026. Clin Immunol. 282:110637. doi: 10.1016/j.clim.2025.110637.

Woessner NM, Keller B, Minguet S. 2025. LCK at the crossroad of immunodeficiency and autoimmunity: Mechanisms and therapeutic opportunities. Immunol Lett. 2025 279:107126. doi: 10.1016/j.imlet.2025.107126.

Srinivasan S, Subramanian S, Zhou H, Hoppmann A, Metzger P, Boerries M, Ramamoorthy S. 2025. Synonymous and non-synonymous variants at splice junctions can disrupt splicing and are frequently linked to disease associated loss of function genes. BMC Genomics. Dec 23. doi: 10.1186/s12864-025-12466-0.

Grün S, Rensing-Ehl A, Suske T, Wolter-Mess J, Gehrig J, Mann J, König C, Hauri M, Heeg M, Leahy TR, Genevieve D, Gaillard JB, Broly M, Bourdin A, Castro C, Seidel L, Bengsch B, Aichele P, Weißert K, Fernandez-Orth J, Schipperges V, Andrieux G, Boerries M, Cabezas-Wallscheid N, Erlacher M, Elling R, Speckmann C, Heller L, Schulte B, Lorenz M, Schwarz K, Moriggl R, Ehl S. Somatic STAT5BN642H mutations shape variable immune landscapes resulting in heterogenous immune diseases. 2025. J Allergy Clin Immunol. S0091-6749(25)02190-6. doi: 10.1016/j.jaci.2025.12.993.

Shimizu T, Prinz M. 2025. Microglia across evolution: from conserved origins to functional divergence. Cell Mol Immunol. 22(12):1533-1548. doi: 10.1038/s41423-025-01368-6.

Pannhausen J, Chughtai AA, Yüce CL, Melzer MK, Ma Y, Seillier L, van der Vorst EPC, Andrieux G, Wirtz J, Leypold S, Kühnel MP, Hoffmann P, Heilmann-Heimbach S, Boerries M, Kleger A, Saar M, Eble MJ, Jonigk DD, Gaisa NT, Rose M. 2025. Targeting ATR offers multifaceted treatment strategies involving RAD51-mediated compensatory DNA repair in bladder cancer. J Exp Clin Cancer Res. doi: 10.1186/s13046-025-03603-4.

Rassner M, Müller TA, Crossley KA, Andrieux G, Schaberg S, Endres C, Jakob L, Poggio T, Köhler N, Kolter J, Müller-Newen G, Schönberger K, Cabezas-Wallscheid N, Gonzalez-Menendez I, Quintanilla-Martinez L, Zwick M, Ashok D, Hartmann TN, Groß O, Gorka O, Follo M, Illert AL, Boerries M, Zeiser R, Duyster J. 2025. Oncostatin M induced by STAT5-activating oncogenes promotes disease progression in hematologic malignancies. Signal Transduct Target Ther. 2025 Dec 11;10(1):400. doi: 10.1038/s41392-025-02491-6.

Wissemann J, Heidenreich A, Suchanek D, Koentges C, Engelmann J, Jung M, Karnbrock L, Marchini T, Pospisilik A, Seifert G, Groß O, Gissler MC, Hilgendorf I, von Zur Mühlen C, Zirlik A, Westermann D, Stachon P, Wolf D, Merz J. 2025. Externalized Inflammasomes in Visceral Fat Sustain Obesity-Related Inflammation. Circ Res. 137(12):1543-1545. doi: 10.1161/CIRCRESAHA.125.327146.

Friedmann D, Payne KJ, Cousin V, Andrieux G, Meng K, Schlaak AE, Unger S, Klocperk A, Geier C, Gräwe K, Pfeiffer J, Jakob TF, Hausmann O, Anhut P, Shabani M, Kurowski K, Rogg M, Aumann K, Seidl M, Provaznik J, Benes V, Boerries M, Boettler T, Schell C, Goldacker S, Keller B, Bengsch B, Warnatz K. 2025. Expansion of a distinct cytotoxic CD4 TFH-cell cluster in lymph nodes of patients with complicated Common Variable Immunodeficiency. J Allergy Clin Immunol. 2025 Nov 26:S0091-6749(25)01144-3. doi: 10.1016/j.jaci.2025.09.032.

Thimme R, Hofmann M, Bertoletti A, Le Bert N. 2025. Decoding HBV-specific adaptive immunity: from natural clearance to cure. Gut. Nov 28:gutjnl-2025-337129. doi: 10.1136/gutjnl-2025-337129.

Rogg M, Weißer L, Maier JI, Sigle A, Helmstädter M, Stigler M, Sammarco A, Gräwe K, Andreev G, Kark C, Ramakrishnan SK, Özel C, Butt L, Arnold F, Bechtel-Walz W, Schilling O, Tanriver Y, Brinkkötter P, Grabbert M, Simons M, Werner M, Kretz O, Benzing T, Huber TB, Schell C. 2025. Arp2/3-dependent regulation of ciliogenesis governs adaptive distal tubular epithelial cell states in kidney disease. Sci Adv. 11(48):eady1623. doi: 10.1126/sciadv.ady1623.

Camacho-Ordonez N, Hirsch A, Campos L, Goldacker S, Burns SO, Moreira F, Warnatz K, Grimbacher B. Do CVID patients on SCIG have more autoimmune (thrombo)cytopenic events than CVID patients on IVIG? 2025. Front Immunol. 16:1708813. doi: 10.3389/fimmu.2025.1708813.

Giuliani C, Benadi G, Engel F, Werner J, Watter M, Schwarzer G, Groß O, Zeiser R, Binder H, Kaier K. Identifying Biomedical Entities for Datasets in Scientific Articles: 4-Step Cache-Augmented Generation Approach Using GPT-4o and PubTator 3.0. 2025. JMIR Form Res. 9:e73822. doi: 10.2196/73822.

Liu J, Rogg M, Moos K, Sasanpour S, Strassl V, Jain M, Magassa S, Neubauer B, Braeg S, Saller BS, Weißer L, Bienaimé F, Gorka O, Boerries M, Viau A, Gross O, Schell C, Kuehn EW. 2025. Inhibition of the inflammasome ameliorates orthologous polycystic kidney disease. Proc Natl Acad Sci U S A. 122(46):e2511204122. doi: 10.1073/pnas.2511204122.

Liu J, Rogg M, Moos K, Sasanpour S, Strassl V, Jain M, Magassa S, Neubauer B, Braeg S, Saller BS, Weißer L, Bienaimé F, Gorka O, Boerries M, Viau A, Gross O, Schell C, Kuehn EW.2025. Inhibition of the inflammasome ameliorates orthologous polycystic kidney disease. Proc Natl Acad Sci U S A. 122(46):e2511204122. doi: 10.1073/pnas.2511204122.