Anne Rensing-Ehl

Dr.
Principal Investigator

Institute for Immunodeficiency (IFI)
Center for Chronic Immunodeficiency (CCI)
Medical Center – University of Freiburg

Breisacher Str. 115
D-79106 Freiburg

Current position

Group leader, Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center – University of Freiburg

Academic training

1985 - 1992 Study of Medicine in Aachen, Erlangen and Munich

Scientific qualifications

1992 Dissertation in Medicine, University of Erlangen
(Supervisor: Prof. Dr. G. Burmester)

Postgraduate Positions

since 2022 Group leader, Institute for Immunodeficiency, Medical Center – University of Freiburg
2008 - 2022 Postdoctorate in part time, Center for Chronic Immunodeficiency, Medical Center - University of Freiburg
2005 - 2008 Postdoctorate in part time, Department of Dermatology, University of Freiburg
1994 - 1995 Postdoctorate, Institute for Clinical Immunology, University of Zurich, Switzerland
1993 - 1994 Postdoctorate, Institute for Immunology, University of Munich

link to all publications from A. Rensing-Ehl: Pubmed

Publications based on CRC1160 funding

Hägele P, Staus P, Scheible R, Uhlmann A, Heeg M, Klemann C, Maccari ME, Ritterbusch H, Armstrong M, Cutcutache I, Elliott KS, von Bernuth H, Leahy TR, Leyh J, Holzinger D, Lehmberg K, Svec P, Masjosthusmann K, Hambleton S, Jakob M, Sparber-Sauer M, Kager L, Puzik A, Wolkewitz M, Lorenz MR, Schwarz K, Speckmann C, Rensing-Ehl A, Ehl S; ALPID study group. 2024. Diagnostic evaluation of paediatric autoimmune lymphoproliferative immunodeficiencies (ALPID): a prospective cohort study. Lancet Haematol. 11(2):e114-e126. doi: 10.1016/S2352-3026(23)00362-9.

Staniek J, Kalina T, Andrieux G, Boerries M, Janowska I, Fuentes M, Díez P, Bakardjieva M, Stancikova J, Raabe J, Neumann J, Schwenk S, Arpesella L, Stuchly J, Benes V, García Valiente R, Fernández García J, Carsetti R, Piano Mortari E, Catala A, de la Calle O, Sogkas G, Neven B, Rieux-Laucat F, Magerus A, Neth O, Olbrich P, Voll RE, Alsina L, Allende LM, Gonzalez-Granado LI, Böhler C, Thiel J, Venhoff N, Lorenzetti R, Warnatz K, Unger S, Seidl M, Mielenz D, Schneider P, Ehl S, Rensing-Ehl A, Smulski CR, Rizzi M. 2024. Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells. Sci Immunol. Jan 12;9(91):eadj5948. doi: 10.1126/sciimmunol.adj5948.

Rensing-Ehl, A., M. R. Lorenz, M. Fuhrer, W. Willenbacher, E. Willenbacher, S. Sopper, M. Abinun, M. E. Maccari, C. Konig, P. Haegele, S. Fuchs, C. Castro, P. Kury, O. Pelle, C. Klemann, M. Heeg, J. Thalhammer, O. Wegehaupt, M. Fischer, S. Goldacker, B. Schulte, S. Biskup, P. Chatelain, V. Schuster, K. Warnatz, B. Grimbacher, A. Meinhardt, D. Holzinger, P. T. Oommen, T. Hinze, H. Hebart, K. Seeger, K. Lehmberg, T. R. Leahy, A. Claviez, S. Vieth, F. H. Schilling, I. Fuchs, M. Gross, F. Rieux-Laucat, A. Magerus, C. Speckmann, K. Schwarz, S. Ehl, and A. s. group. 2023. Abnormal biomarkers predict complex FAS or FADD defects missed by exome sequencing. J Allergy Clin Immunol. doi:10.1016/j.jaci.2023.11.006.

Magerus, A., A. Rensing-Ehl, V. K. Rao, D. Teachey, F. Rieux-Laucat, and S. Ehl. 2023. Autoimmune-lymphoproliferative immunodeficiencies (ALPID) A proposed approach to redefining ALPS and other lymphoproliferative immune disorders. J Allergy Clin Immunol. doi:10.1016/j.jaci.2023.11.004.

Cox EM, El-Behi M, Ries S, Vogt JF, Kohlhaas V, Michna T, Manfroi B, Al-Maarri M, Wanke F, Tirosh B, Pondarre C, Lezeau H, Yogev N, Mittenzwei R, Descatoire M, Weller S, Weill JC, Reynaud CA, Boudinot P, Jouneau L, Tenzer S, Distler U, Rensing-Ehl A, König C, Staniek J, Rizzi M, Magérus A, Rieux-Laucat F, Wunderlich FT, Hövelmeyer N, Fillatreau S. 2023.  AKT activity orchestrates marginal zone B cell development in mice and humans. Cell Rep. 2023 Apr 14;42(4):112378. doi: 10.1016/j.celrep.2023.112378.