Center for Medicine
Department for Pathology
Institute for Surgical Pathology
Breisacher Str. 115A
79106 Freiburg
- +49 (0) 761 / 270-80650; -80400
- christoph.schell@uniklinik-freiburg.de
- Homepage
Current Position
Pathology Resident, Group Leader and Clinician-Scientist at the Institute of Surgical Pathology, Medical Center – University of Freiburg
Academic training
2011 - 2014 | PhD at SGBM graduate school, University of Freiburg |
2002 - 2008 | Medical School, LMU and TU Munich |
Scientific training
2020 | Habilitation in Experimental Pathology, University of Freiburg (Mentor: Prof. Dr. M. Werner & Prof. Dr. T. Huber) |
2014 | Dissertation (Dr. rer. nat.), Faculty of Biology, University of Freiburg (Supervisor: Prof. Dr. T. Huber) |
2012 | Dissertation (Dr. med.) LMU University of Munich (Supervisor: Prof. Dr. A. Mayrhofer) |
Postgraduate positions
2017 - present | Group Leader, Institute of Surgical Pathology, Medical Center - University of Freiburg |
2016 - present | Pathology Resident, Institute of Surgical Pathology, Medical Center - University of Freiburg |
2014 - 2015 | Junior Group Leader, Department of Nephrology, Medical Center - University of Freiburg |
2011 - 2015 | Reserach Fellow, Department of Nephrology, Medical Center - University of Freiburg |
2010- 2011 | Internal Medicine Residency, Medical Center - University of Freiburg |
2009 - 2010 | Internal Medicine Residency, Medical Center - University of Freiburg |
Miscellaneous (Honors, Awards)
2017 - 2020 | Berta-Ottenstein Clinician Scientist Fellow |
2014 | Research Stipend – German Society of Nephrology |
2013 - 2014 | Clinician Scientist Fellowship – NAKSYS (EKFS) |
link to all publications from C. Schell: Pubmed
Publications based on CRC1160 funding
Dettmer-Monaco V, Weißert K, Ammann S, Monaco G, Lei L, Gräßel L, Rhiel M, Rositzka J, Kaufmann MM, Geiger K, Andrieux G, Lao J, Thoulass G, Schell C, Boerries M, Illert AL, Cornu TI, Ehl S, Aichele P, Cathomen T. 2024. Gene editing of hematopoietic stem cells restores T-cell response in familial hemophagocytic lymphohistiocytosis. J Allergy Clin Immunol. Jan;153(1):243-255.e14. doi: 10.1016/j.jaci.2023.08.003.
Rogg M, Maier JI, Helmstädter M, Sammarco A, Kliewe F, Kretz O, Weißer L, Van Wymersch C, Findeisen K, Koessinger AL, Tsoy O, Baumbach J, Grabbert M, Werner M, Huber TB, Endlich N, Schilling O, Schell C. 2023. A YAP/TAZ-ARHGAP29-RhoA Signaling Axis Regulates Podocyte Protrusions and Integrin Adhesions. Cells. 2023 Jul 6;12(13):1795. doi: 10.3390/cells12131795.
Strohmeier V, Andrieux G, Unger S, Pascual-Reguant A, Klocperk A, Seidl M, Marques OC, Eckert M, Gräwe K, Shabani M, von Spee-Mayer C, Friedmann D, Harder I, Gutenberger S, Keller B, Proietti M, Bulashevska A, Grimbacher B, Provaznik J, Benes V, Goldacker S, Schell C, Hauser AE, Boerries M, Hasselblatt P, Warnatz K. 2023. Interferon-Driven Immune Dysregulation in Common Variable Immunodeficiency-Associated Villous Atrophy and Norovirus Infection. J Clin Immunol. 43(2):371-390. doi: 10.1007/s10875-022-01379-2.
Ruckert, T., G. Andrieux, M. Boerries, K. Hanke-Muller, N. M. Woessner, S. Doetsch, C. Schell, K. Aumann, J. Kolter, A. Schmitt-Graeff, M. Schiff, L. M. Braun, E. Haring, S. Kissel, B. A. Siranosian, A. S. Bhatt, P. Nordkild, J. Wehkamp, B. A. H. Jensen, S. Minguet, J. Duyster, R. Zeiser, and N. Kohler. 2022. Human beta-defensin 2 ameliorates acute GVHD by limiting ileal neutrophil infiltration and restraining T cell receptor signaling. Sci Transl Med 14: eabp9675. doi: 10.1126/scitranslmed.abp9675.
Weissert, K., S. Ammann, T. Kogl, V. Dettmer-Monaco, C. Schell, T. Cathomen, S. Ehl, and P. Aichele. 2022. Adoptive T cell therapy cures mice from active hemophagocytic lymphohistiocytosis (HLH). EMBO Mol Med: e16085. doi: 10.15252/emmm.202216085.
Strohmeier, V., G. Andrieux, S. Unger, A. Pascual-Reguant, A. Klocperk, M. Seidl, O. C. Marques, M. Eckert, K. Grawe, M. Shabani, C. von Spee-Mayer, D. Friedmann, I. Harder, S. Gutenberger, B. Keller, M. Proietti, A. Bulashevska, B. Grimbacher, J. Provaznik, V. Benes, S. Goldacker, C. Schell, A. E. Hauser, M. Boerries, P. Hasselblatt, and K. Warnatz. 2022. Interferon-Driven Immune Dysregulation in Common Variable Immunodeficiency-Associated Villous Atrophy and Norovirus Infection. J Clin Immunol. pii: 10.1007/s10875-022-01379-2. doi: 10.1007/s10875-022-01379-2.
Globig AM, Mayer LS, Heeg M, Andrieux G, Ku M, Otto-Mora P, Hipp A, Zoldan K, Pattekar A, Rana N, Schell C, Boerries M, Hofmann M, Neumann-Haefelin C, Kuellmer A, Schmidt A, Boettler T, Tomov V, Thimme R, Hasselblatt P, Bengsch B. Gastroenterology. 2022. Exhaustion of CD39-expressing CD8+ T cells in Crohn’s disease is linked to clinical outcome. First published: 2022 Jun 20:S0016-5085(22)00663-1. doi: 10.1053/j.gastro.2022.06.045. Online ahead of print.