Hanspeter Pircher


Department for Medical Microbiology and Hygiene
Institute for Immunology
Medical Center – University of Freiburg

Hermann Herder Str. 11
79104 Freiburg i. Brsg.

Current position

Professor, Head of the Institute for Immunology, Center for Microbiology and Hygiene, Medical Center – University of Freiburg

Academic training

1976 – 1981 Study of Biochemistry, ETH Zurich, Switzerland

Scientific qualifications

1993 Habilitation in Exp. Immunology, University of Zurich, Switzerland (Mentor: Prof. Rolf Zinkernagel)
1985 PhD Thesis, ETH/University Hospital Zurich, Switzerland (Supervisor: Prof. Hans Hengartner)

Postgraduate Positions

since 1995 C3 Professor and Head of the Institute for Immunology, Center for Microbiology and Hygiene, Medical Center – University of Freiburg
1988 – 1995 Research Fellow, Institute of Experimental Immunology,
University of Zurich, Switzerland
1986 – 1987 Postdoctorate, Ontario Cancer Institute, Toronto, Canada

Miscellaneous (Honors, Awards)

2015 - 2017 Deputy Speaker SFB 1160
2009 – 2013 Speaker SFB 620
2002 – 2009 Deputy Speaker SFB 620

Publications based on CRC1160 funding

Gather, R., P. Aichele, N. Goos, J. Rohr, H. Pircher, T. Kogl, R. Zeiser, H. Hengel, A. Schmitt-Graff, C. Weaver, and S. Ehl. 2020. Trigger-dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis. Eur J Immunol. doi: 10.1002/eji.201948123. [Epub ahead of print].

Schweier, O., U. Aichele, A. F. Marx, T. Straub, J. S. Verbeek, D. D. Pinschewer, and H. Pircher. 2019. Residual LCMV antigen in transiently CD4(+) T cell-depleted mice induces high levels of virus-specific antibodies but only limited B-cell memory.  Eur J Immunol 49: 626-637.

Straub T, Pircher H. 2019. Enhancing immunity prevents virus-induced T-cell-mediated immunopathology in B cell-deficient mice. Eur J Immunol. 49(5):782-789.

Schuch A, Zecher BF, Müller PA, Correia MP, Daul F, Rennert C, Tauber C, Schlitt K, Boettler T, Neumann-Haefelin C, Hengel H, Pircher H, Cerwenka A, Thimme R, Hofmann M. 2019. NK-cell responses are biased towards CD16-mediated effector functions in chronic hepatitis B virus infection. J Hepatol. 70(3):351-360.

Straub, T., M. A. Freudenberg, U. Schleicher, C. Bogdan, G. Gasteiger, and Pircher. 2018. Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells. Nat Commun 9: 4117.

Hofmann, M., D. Wieland, Pircher, and R. Thimme. 2018. Memory vs memory-like: The different facets of CD8(+) T-cell memory in HCV infection. Immunol Rev 283: 232-237.

Woopen C, Straub T, Schweier O, Aichele U, Düker K, Boehm T, Pircher H. 2018. Immunological tolerance to LCMV antigens differently affects control of acute and chronic virus infection in mice. Eur J Immunol. 48(1):120-127.