Jan Rohr

Principal Investigator
(Alumni)

Center for Pediatrics
Department of General Pediatrics, Adolescent Medicine and Neonatology &
Center for Chronic Immunodeficiency
Medical Center – University of Freiburg

Breisacher Str. 117, 2.OG
79106 Freiburg i. Brsg.

Current position

Assistant physician and Junior Group leader, Center for Pediatrics and Center for Chronic Immunodeficiency, Medical Center – University of Freiburg

Academic training

1997 – 2004 Study of Medicine in Greifswald, Homburg and Heidelberg

Scientific qualifications

2004 Dissertation in Medicine, University of Mainz
(Supervisor: Prof. F. Zepp)

Postgraduate Positions

since 2014 Assistant physician and Junior Group leader, Center for Pediatrics and Center for Chronic Immunodeficiency,
Medical Center - University of Freiburg
2010 – 2013 Postdoctorate, Department of Immunology, The Netherlands Cancer Institute (NKI-AVL), Amsterdam, The Netherlands
2004 – 2010 Assistant physician in Division of General Pediatrics and Adolescent Medicine, Medical Center - University of Freiburg

Miscellaneous (Honors, Awards)

2011 Research Fellowship (Deutsche Forschungsgemeinschaft (DFG))
2010 Walter-Hitzig Fellowship (Center for Chronic Immunodeficiency, Freiburg)

Publications based on CRC1160 funding

Gather, R., P. Aichele, N. Goos, J. Rohr, H. Pircher, T. Kogl, R. Zeiser, H. Hengel, A. Schmitt-Graff, C. Weaver, and S. Ehl. 2020. Trigger-dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis. Eur J Immunol. doi: 10.1002/eji.201948123. [Epub ahead of print].

Zenke S, Palm MM, Braun J, Gavrilov A, Meiser P, Böttcher JP, Beyersdorf N, Ehl S, Gerard A, Lämmermann T, Schumacher TN, Beltman JB, Rohr JC. 2020. Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics. Immunity. 52(2):313-327.e7.

Prestipino A, Emhardt AJ, Aumann K, O’Sullivan D, Gorantla SP, Duquesne S,Melchinger W, Braun L, Vuckovic S, Boerries M, Busch H, Halbach S, Pennisi S, Poggio T, Apostolova P, Veratti P, Hettich M, Niedermann G, Bartholomä M,Shoumariyeh K, Jutzi JS, Wehrle J, Dierks C, Becker H, Schmitt-Graeff A, Follo M, Pfeifer D, Rohr J, Fuchs S, Ehl S, Hartl FA, Minguet S, Miething C, Heidel FH, Kröger N, Triviai I, Brummer T, Finke J, Illert AL, Ruggiero E, Bonini C, Duyster J, Pahl HL, Lane SW, Hill GR, Blazar BR, von Bubnoff N, Pearce EL, Zeiser R. 2018. Oncogenic JAK2(V617F) causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms. Sci Transl Med. 10(429). pii:eaam7729.

Klemann C, Ammann S, Heizmann M, Fuchs S, Bode SF, Heeg M, Fuchs H, Lehmberg K, Zur Stadt U, Roll C, Vraetz T, Speckmann C, Lorenz MR, Schwarz K, Rohr J, Feske S, Ehl S. 2017. Hemophagocytic lymphohistiocytosis as presenting manifestation of profound combined immunodeficiency due to an ORAI1 mutation. J Allergy Clin Immunol. 140(6):1721-1724.