Institute for Infection Prevention and Control
Medical Center – University of Freiburg
Breisacher Str. 113
79106 Freiburg i. Brsg.
- +49 (0) 761/ 270 – 82730
- katrin.kierdorf@uniklinik-freiburg.de
- Homepage
Current position
Juniorprofessor for Neuroimmunology, Institute for Infection Prevention and Control, Medical Center – University of Freiburg
Academic training
| 2004 – 2008 | Molecular Biomedicine (Diploma studies), University of Bonn, Bonn, Germany |
Scientific qualifications
| 2013 | Dr. rer. nat., Molecular Medicine, University of Freiburg, Freiburg im Breisgau, Germany |
Postgraduate Positions
| since 2025 | W1 Professor for Neuroimmunology, Institute for Infection Prevention and Control, Medical Center - University of Freiburg, Germany |
| Since 11/2017 | W1 Professor for Neuroimmunology, Institute of Neuropathology, University of Freiburg, Germany |
| 2015–2017 | Research Associate, Prof. Dr. Marc S. Dionne, MRC Centre for Molecular Bacteriology and Infection, Imperial College London, United Kingdom |
| 2013–2015 | Research Associate, Prof. Dr. Frederic Geissmann, Centre for Molecular and Cellular Biology of Inflammation, King’s College London, United Kingdom |
| 2013 | Research Associate, Prof. Dr. Marco Prinz, Institute of Neuropathology, University Freiburg, Germany |
Miscellaneous (Honors, Awards)
| 2022 | Awardee Rising Star Initiative, ONO Pharmaceutical Co., Ltd. |
| 2014-2016 | Postdoctoral Fellowship, German Research Foundation (DFG) |
| 2014 | GeFI Award Recipient, Freiburg |
| 2013 | Herbert-Fischer-Award, German Society of Immunology (DGfI) |
link to all publications from K. Kierdorf: Pubmed
Publications based on CRC1160 funding
Petry P, Oschwald A, Merkt S, Dinh TJ, Andrieux G, Crisand C, Botterer H, Nent E, Paterson N, Havermans M, Sankowski R, Schilling O, Boerries M, Amann L, Groß O, Schlitzer A, Prinz M, Lämmermann T, Kierdorf K. 2025. Early microglia progenitors colonize the embryonic CNS via integrin-mediated migration from the pial surface. Dev Cell. S1534-5807(25)00532-5. doi: 10.1016/j.devcel.2025.08.012.
Kolter J, Döring CL, Sarout S, Baasch S, Steele L, Alsumati R, Lucena Silva GV, Aníbal Silva CE, Paiva IM, Mansoori Moghadam Z, Gres V, Lohrmann F, Aktories P, Buchegger T, Bijnen M, Doumard L, Voisin B, Le Foll C, Lachmann N, Greter M, Kierdorf K, Haniffa M, Cunha TM, Flacher V, Henneke P. 2025. Sensory neurons shape local macrophage identity via TGF-β signaling. Immunity. 2025 Sep 5:S1074-7613(25)00367-X. doi: 10.1016/j.immuni.2025.08.004.
Ardura-Fabregat A, Bosch LFP, Wogram E, Mossad O, Sankowski R, Aktories P, Kieger L, Cook J, Hasavci D, Ulupinar H, Brock D, Wang F, Iovino N, Wald S, Preissl S, Yilmaz B, Schnepf D, Macpherson AJ, Blank T, Kierdorf K, Prinz M. 2025. Response of spatially defined microglia states with distinct chromatin accessibility in a mouse model of Alzheimer’s disease. Nat Neurosci. 28(8):1688-1703. doi: 10.1038/s41593-025-02006-0.
Saller BS, Wöhrle S, Fischer L, Dufossez C, Ingerl IL, Kessler S, Mateo-Tortola M, Gorka O, Lange F, Cheng Y, Neuwirt E, Marada A, Koentges C, Urban C, Aktories P, Reuther P, Giese S, Kirschnek S, Mayer C, Pilic J, Falquez-Medina H, Oelgeklaus A, Deepagan VG, Shojaee F, Zimmermann JA, Weber D, Tai YH, Crois A, Ciminski K, Peyronnet R, Brandenburg KS, Wu G, Baumeister R, Heimbucher T, Rizzi M, Riedel D, Helmstädter M, Buescher J, Neumann K, Misgeld T, Kerschensteiner M, Walentek P, Kreutz C, Maurer U, Rambold AS, Vince JE, Edlich F, Malli R, Häcker G, Kierdorf K, Meisinger C, Köttgen A, Jakobs S, Weber ANR, Schwemmle M, Groß CJ, Groß O. 2024. Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation. Immunity. S1074-7613(24)00492-8. doi: 10.1016/j.immuni.2024.10.012.
Petry P, Aktories P, Oschwald A, Kierdorf K. 2024. Protocol for long-term monocultures of murine macrophages derived from distinct adult tissues. STAR Protoc. 5(3):103145. doi: 10.1016/j.xpro.2024.103145.
Vinnakota JM, Biavasco F, Schwabenland M, Chhatbar C, Adams RC, Erny D, Duquesne S, El Khawanky N, Schmidt D, Fetsch V, Zähringer A, Salié H, Athanassopoulos D, Braun LM, Javorniczky NR, Ho JNHG, Kierdorf K, Marks R, Wäsch R, Simonetta F, Andrieux G, Pfeifer D, Monaco G, Capitini C, Fry TJ, Blank T, Blazar BR, Wagner E, Theobald M, Sommer C, Stelljes M, Reicherts C, Jeibmann A, Schittenhelm J, Monoranu CM, Rosenwald A, Kortüm M, Rasche L, Einsele H, Meyer PT, Brumberg J, Völkl S, Mackensen A, Coras R, von Bergwelt-Baildon M, Albert NL, Bartos LM, Brendel M, Holzgreve A, Mack M, Boerries M, Mackall CL, Duyster J, Henneke P, Priller J, Köhler N, Strübing F, Bengsch B, Ruella M, Subklewe M, von Baumgarten L, Gill S, Prinz M, Zeiser R. 2024. Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome. Nat Cancer. May 13. doi: 10.1038/s43018-024-00764-7.
Hersperger F, Meyring T, Weber P, Chhatbar C, Monaco G, Dionne MS, Paeschke K, Prinz M, Groß O, Classen AK, Kierdorf K. 2024. DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress. Elife. 2024 Jan 8;12:RP86700. doi: 10.7554/eLife.86700.
Mass E, Nimmerjahn F, Kierdorf K, Schlitzer A. 2023. Tissue-specific macrophages: how they develop and choreograph tissue biology. Nat Rev Immunol. Mar 15:1-17. doi: 10.1038/s41577-023-00848-y.
