Peter Stäheli

Principal Investigator
(Alumni)

Department for Medical Microbiology and Hygiene
Institute for Virology
Medical Center – University of Freiburg

Hermann Herder Str. 11
79104 Freiburg i. Brsg.

Current position

Professor, Institute for Virology, Center for Microbiology and Hygiene, Medical Center – University of Freiburg

Academic training

1973 – 1977 Studies of Microbiology and Biochemistry, ETH Zurich, Switzerland

Scientific qualifications

1990 Habilitation in Virology, University of Zurich, Switzerland
(Mentor: Prof. Jean Lindenmann)
1977 – 1981 PhD Thesis, Institute for Microbiology, ETH Zurich, Switzerland (Supervisor: Prof. Ralf Hütter)

Postgraduate Positions

since 1990 C3 Professor, Institute for Virology, Center for Microbiology and Hygiene, Medical Center – University of Freiburg
1985 – 1987 Postdoctorate, Research Institute of Scripps Clinic, La Jolla, CA, USA
1983 – 1985 Visiting Scientist at the Institute for Molecular Biology I, University of Zurich, Switzerland
1982 Internship in Molecular Biology as Visiting Scientist at E.I. du Pont de Nemours & Co., Wilmington, DE, USA
1981 – 1985 Postdoctorate, Institute for Immunology and Virology, University of Zurich, Switzerland

Miscellaneous (Honors, Awards)

2008 Milstein Award from the International Society for Interferon and Cytokine Research
1992 European Award for Interferon Research, Friends of the Hannover Medical School
1992 Award and Gold Medal, Foundation for Research in Science and the Humanities at the University of Zurich, Switzerland

Publications based on CRC1160 funding

Mezö C, Dokalis N, Mossad O, Staszewski O, Neuber J, Yilmaz B, Schnepf D, de Agüero MG, Ganal-Vonarburg SC, Macpherson AJ, Meyer-Luehmann M, Staeheli P, Blank T, Prinz M, Erny D. 2020. Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer’s disease. Acta Neuropathol Commun. 8(1):119. doi: 10.1186/s40478-020-00988-5.

Gebhardt, A., V. Bergant, D. Schnepf, M. Moser, A. Meiler, D. Togbe, C. Mackowiak, L. S. Reinert, S. R. Paludan, B. Ryffel, A. Stukalov, P. Staeheli, and A. Pichlmair. 2019. The alternative cap-binding complex is required for antiviral defense in vivo. PLoS Pathog 15: e1008155.

Lee, S., A. Ishitsuka, M. Noguchi, M. Hirohama, Y. Fujiyasu, P. P. Petric, Schwemmle, P. Staeheli, K. Nagata, and A. Kawaguchi. 2019. Influenza restriction factor MxA functions as inflammasome sensor in the respiratory epithelium. Sci Immunol 4.

Bradley KC, Finsterbusch K, Schnepf D, Crotta S, Llorian M, Davidson S, Fuchs SY, Staeheli P, Wack A. 2019. Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection. Cell Rep. 28(1):245-256.

Holze C, Michaudel C, Mackowiak C, Haas DA, Benda C, Hubel P, Pennemann FL, Schnepf D, Wettmarshausen J, Braun M, Leung DW, Amarasinghe GK, Perocchi F, Staeheli P, Ryffel B, Pichlmair A. 2018. Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway. Nat Immunol. 19(2):130-140. Epub 2017 Dec 18.

Deeg CM, Hassan E, Mutz P, Rheinemann L, Götz V, Magar L, Schilling M, Kallfass C, Nürnberger C, Soubies S, Kochs G, Haller O, Schwemmle M, Staeheli P. 2017. In vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein. J Exp Med. 214(5):1239-1248.

Pillai PS, Molony RD, Martinod K, Dong H, Pang IK, Tal MC, Solis AG, Bielecki P, Mohanty S, Trentalange M, Homer RJ, Flavell RA, Wagner DD, Montgomery RR, Shaw AC, Staeheli P, Iwasaki A. 2016. Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease. Science. 352:463-466.