Toni Cathomen

Principal Investigator

Institute for Transfusion Medicine and Gene Therapy &
Center for Chronic Immunodeficiency
Medical Center – University of Freiburg

Hugstetter Straße 55
79106 Freiburg i. Brsg.

Current position

Professor and Director, Institute for Transfusion Medicine and Gene Therapy,
Medical Center – University of Freiburg

Academic training

1987 – 1992 Study of Biology (Diploma), University of Zurich, Switzerland

Scientific qualifications

1992 – 1997 PhD Thesis in Molecular Biology, University of Zurich, Switzerland (Supervisor: Prof. Dr. Martin A. Billeter)

Postgraduate Positions

since 2012 Director, Institute for Transfusion Medicine and Gene Therapy, Medical Center - University of Freiburg,
Professor of Cell and Gene Therapy, University of Freiburg
2009 – 2012 Associate Professor of Experimental Hematology,
Hannover Medical School
2003 – 2009 Assistant Professor of Molecular Virology, Charité Medical School, Berlin
2002 – 2003 Senior Research Associate, The Salk Institute, San Diego, USA
1998 – 2002 Postdoctorate, The Salk Institute, San Diego, USA
1997 – 1998 Postdoctorate, University of Zurich, Switzerland

Miscellaneous (Honors, Awards)

2021 - 2022 President of the German Society for Gene Therapy (DG-GT e.V.)
2015 Emil-von-Behring Award, German Society for Transfusion Medicine and Immunohematology
1999 - 2001 Fellowship from the Swiss National Science Foundation
1998 - 1999 Fellowship from the Swiss Academy of Medical Sciences
1996 Junior Award, Union of the Swiss Societies for Experimental Biology

link to all publications from T. Cathomen: Pubmed

Publications based on CRC1160 funding

Dettmer, V., K. Bloom, M. Gross, K. Weissert, Aichele, S. Ehl, and T. Cathomen. 2019. Retroviral UNC13D gene transfer restores cytotoxic activity of T cells derived from familial hemophagocytic lymphohistiocytosis type 3 patients in vitro. Hum Gene Ther. 30(8): 975-984.

Simone A. Haas, Viviane Dettmer, Toni Cathomen, Hämostaseologie 2017;37: 45–52

Mussolino C, Alzubi J, Pennucci V, Turchiano G, Cathomen T. 2017. Genome and Epigenome Editing to Treat Disorders of the Hematopoietic System. Hum Gene Ther. 28(11):1105-1115.

Dettmer V, Cathomen T, and Hildenbeutel M. 2017. Genom-Editierung – neue Wege im klinischen Alltag (Review). BIOspektrum 23, 155-8.

Cornu TI, Mussolino C, Cathomen T. 2017. Refining strategies to translate genome editing to the clinic. Nat Med. 23(4):415-423. Review.

Mussolino C, Mlambo T, Cathomen T. 2015. Proven and novel strategies for efficient editing of the human genome. Curr Opin Pharmacol.  24:105-12.