Publications

Fliegauf, M., and Grimbacher. 2018. Nuclear factor kappaB mutations in human subjects: The devil is in the details. J Allergy Clin Immunol 142: 1062-1065.

Locatelli, G., D. Theodorou, A. Kendirli, M. J. C. Jordao, O. Staszewski, K. Phulphagar, L. Cantuti-Castelvetri, A. Dagkalis, A. Bessis, M. Simons, F. Meissner, Prinz, and M. Kerschensteiner. 2018. Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model. Nat Neurosci 21: 1196-1208.

Dudek, A. H., F. Pfaff, H. Bolte, C. W. Kontchou, and Schwemmle. 2018. Partial inactivation of the chromatin remodelers SMARCA2 and SMARCA4 in virus-infected cells by caspase-mediated cleavage. J Virol. 92 pii: e00343-18. doi: 10.1128/JVI.00343-18.

Heeg, M., S. Ammann, C. Klemann, M. Panning, V. Falcone, H. Hengel, K. Lehmberg, U. Zur Stadt, K. Wustrau, G. Janka, and Ehl. 2018. Is an infectious trigger always required for primary hemophagocytic lymphohistiocytosis? Lessons from in utero and neonatal disease. Pediatr Blood Cancer 65: e27344.

Juraske, C., P. Wipa, A. Morath, J. V. Hidalgo, F. A. Hartl, K. Raute, H. H. Oberg, D. Wesch, Fisch, S. Minguet, S. Pongcharoen, and W. W. Schamel. 2018. Anti-CD3 Fab Fragments Enhance Tumor Killing by Human gammadelta T Cells Independent of Nck Recruitment to the gammadelta T Cell Antigen Receptor. Front Immunol 9: 1579.

Viau, A., F. Bienaime, K. Lukas, A. P. Todkar, M. Knoll, T. A. Yakulov, A. Hofherr, O. Kretz, M. Helmstadter, W. Reichardt, S. Braeg, T. Aschman, A. Merkle, D. Pfeifer, V. I. Dumit, M. C. Gubler, R. Nitschke, T. B. Huber, F. Terzi, J. Dengjel, F. Grahammer, M. Kottgen, H. Busch, M. Boerries, G. Walz, Triantafyllopoulou, and E. W. Kuehn. 2018. Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney. EMBO J 37.

Voet, S., C. Mc Guire, N. Hagemeyer, A. Martens, A. Schroeder, P. Wieghofer, C. Daems, O. Staszewski, L. V. Walle, M. J. C. Jordao, M. Sze, H. K. Vikkula, D. Demeestere, G. Van Imschoot, C. L. Scott, E. Hoste, A. Goncalves, M. Guilliams, S. Lippens, C. Libert, R. E. Vandenbroucke, K. W. Kim, S. Jung, Z. Callaerts-Vegh, P. Callaerts, J. de Wit, M. Lamkanfi, Prinz, and G. van Loo. 2018. A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation. Nat Commun 9: 2036.

Rothhammer, V., D. M. Borucki, E. C. Tjon, M. C. Takenaka, C. C. Chao, A. Ardura-Fabregat, K. A. de Lima, C. Gutierrez-Vazquez, P. Hewson, O. Staszewski, M. Blain, L. Healy, T. Neziraj, M. Borio, M. Wheeler, L. L. Dragin, D. A. Laplaud, J. Antel, J. I. Alvarez, Prinz, and F. J. Quintana. 2018. Microglial control of astrocytes in response to microbial metabolites. Nature 557: 724-728.

Hofmann, M., D. Wieland, Pircher, and R. Thimme. 2018. Memory vs memory-like: The different facets of CD8(+) T-cell memory in HCV infection. Immunol Rev 283: 232-237.

Jung, S., L. Gamez-Diaz, M. Proietti, and Grimbacher. 2018. Immune TOR-opathies, a Novel Disease Entity in Clinical Immunology. Front Immunol 9: 966.

Schwab, C., A. Gabrysch, P. Olbrich, V. Patino, Warnatz, D. Wolff, A. Hoshino, M. Kobayashi, K. Imai, M. Takagi, I. Dybedal, J. A. Haddock, D. Sansom, J. M. Lucena, M. Seidl, A. Schmitt-Graff, V. Reiser, F. Emmerich, N. Frede, A. Bulashevska, U. Salzer, D. Schubert, S. Hayakawa, S. Okada, M. Kanariou, Z. Y. Kucuk, H. Chapdelaine, L. Petruzelkova, Z. Sumnik, A. Sediva, M. Slatter, P. D. Arkwright, A. Cant, H. M. Lorenz, T. Giese, V. Lougaris, A. Plebani, C. Price, K. E. Sullivan, M. Moutschen, J. Litzman, T. Freiberger, F. L. van de Veerdonk, M. Recher, M. H. Albert, F. Hauck, S. Seneviratne, J. P. Schmid, A. Kolios, G. Unglik, C. Klemann, C. Speckmann, S. Ehl, A. Leichtner, R. Blumberg, A. Franke, S. Snapper, S. Zeissig, C. Cunningham-Rundles, L. Giulino-Roth, O. Elemento, G. Duckers, T. Niehues, E. Fronkova, V. Kanderova, C. D. Platt, J. Chou, T. Chatila, R. Geha, E. McDermott, S. Bunn, M. Kurzai, A. Schulz, L. Alsina, F. Casals, A. Deya-Martinez, S. Hambleton, H. Kanegane, K. Tasken, O. Neth, and B. Grimbacher. 2018. Phenotype, penetrance, and treatment of 133 CTLA-4-insufficient individuals. J Allergy Clin Immunol. 142: 1932-1946.

Provine, N. M., B. Binder, M. E. B. FitzPatrick, A. Schuch, L. C. Garner, K. D. Williamson, B. van Wilgenburg, Thimme, P. Klenerman, and M. Hofmann. 2018. Unique and Common Features of Innate-Like Human Vdelta2(+) gammadeltaT Cells and Mucosal-Associated Invariant T Cells. Front Immunol 9: 756.

Mathew NR, Baumgartner F, Braun L, O’Sullivan D, Thomas S, Waterhouse M, Müller TA, Hanke K, Taromi S, Apostolova P, Illert AL, Melchinger W, Duquesne S, Schmitt-Graeff A, Osswald L, Yan KL, Weber A, Tugues S, Spath S, Pfeifer D, Follo M, Claus R, Lübbert M, Rummelt C, Bertz H, Wäsch R, Haag J, Schmidts A, Schultheiss M, Bettinger D, Thimme R, Ullrich E, Tanriver Y, Vuong GL, Arnold R, Hemmati P, Wolf D, Ditschkowski M, Jilg C, Wilhelm K, Leiber C, Gerull S, Halter J, Lengerke C, Pabst T, Schroeder T, Kobbe G, Rösler W, Doostkam S, Meckel S,Stabla K, Metzelder SK, Halbach S, Brummer T, Hu Z, Dengjel J, Hackanson B, Schmid C, Holtick U, Scheid C, Spyridonidis A, Stölzel F, Ordemann R, Müller LP, Sicre-de-Fontbrune F, Ihorst G, Kuball J, Ehlert JE, Feger D, Wagner EM, Cahn JY, Schnell J, Kuchenbauer F, Bunjes D, Chakraverty R, Richardson S, Gill S, Kröger N, Ayuk F, Vago L, Ciceri F, Müller AM, Kondo T, Teshima T, Klaeger S, Kuster B, Kim DDH, Weisdorf D, van der Velden W, Dörfel D, Bethge W, Hilgendorf I, Hochhaus A, Andrieux G, Börries M, Busch H, Magenau J, Reddy P, Labopin M, Antin JH, Henden AS, Hill GR, Kennedy GA, Bar M, Sarma A, McLornan D, Mufti G, Oran B, Rezvani K, Shah O, Negrin RS, Nagler A, Prinz M, Burchert A, Neubauer A, Beelen D, Mackensen A, von Bubnoff N, Herr W, Becher B, Socié G, Caligiuri MA, Ruggiero E, Bonini C, Häcker G, Duyster J, Finke J, Pearce E, Blazar BR, Zeiser R. Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nat Med. 24: 282-291.

Simone A. Haas, Viviane Dettmer, Toni Cathomen, Hämostaseologie 2017;37: 45–52

Tesi B, Rascon J, Chiang SCC, Burnyte B, Löfstedt A, Fasth A, Heizmann M, Juozapaite S, Kiudeliene R, Kvedaraite E, Miseviciene V, Muleviciene A, Müller ML, Nordenskjöld M, Matuzeviciene R, Samaitiene R, Speckmann C, Stankeviciene S, Zekas V, Voss M, Ehl S, Vaiciene-Magistris N, Henter JI, Meeths M, Bryceson YT. 2018. A RAB27A 5′ untranslated region structural variant associated with late-onset hemophagocytic lymphohistiocytosis and normal pigmentation. J Allergy Clin Immunol. 142(1):317-321.e8.

Prestipino A, Emhardt AJ, Aumann K, O’Sullivan D, Gorantla SP, Duquesne S,Melchinger W, Braun L, Vuckovic S, Boerries M, Busch H, Halbach S, Pennisi S, Poggio T, Apostolova P, Veratti P, Hettich M, Niedermann G, Bartholomä M,Shoumariyeh K, Jutzi JS, Wehrle J, Dierks C, Becker H, Schmitt-Graeff A, Follo M, Pfeifer D, Rohr J, Fuchs S, Ehl S, Hartl FA, Minguet S, Miething C, Heidel FH, Kröger N, Triviai I, Brummer T, Finke J, Illert AL, Ruggiero E, Bonini C, Duyster J, Pahl HL, Lane SW, Hill GR, Blazar BR, von Bubnoff N, Pearce EL, Zeiser R. 2018. Oncogenic JAK2(V617F) causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms. Sci Transl Med. 10(429). pii:eaam7729.