Publications

Strohmeier, V., G. Andrieux, S. Unger, A. Pascual-Reguant, A. Klocperk, M. Seidl, O. C. Marques, M. Eckert, K. Grawe, M. Shabani, C. von Spee-Mayer, D. Friedmann, I. Harder, S. Gutenberger, B. Keller, M. Proietti, A. Bulashevska, B. Grimbacher, J. Provaznik, V. Benes, S. Goldacker, C. Schell, A. E. Hauser, M. Boerries, P. Hasselblatt, and K. Warnatz. 2022. Interferon-Driven Immune Dysregulation in Common Variable Immunodeficiency-Associated Villous Atrophy and Norovirus Infection. J Clin Immunol. pii: 10.1007/s10875-022-01379-2. doi: 10.1007/s10875-022-01379-2.

Petric, P. P., J. King, L. Graf, A. Pohlmann, M. Beer, and M. Schwemmle. 2022. Increased Polymerase Activity of Zoonotic H7N9 Allows Partial Escape from MxA. Viruses 14: 2331. doi: 10.3390/v14112331.

Konig, S., M. Fliegauf, M. Rhiel, B. Grimbacher, T. I. Cornu, T. Cathomen, and C. Mussolino. 2022. Allele-Specific Disruption of a Common STAT3 Autosomal Dominant Allele Is Not Sufficient to Restore Downstream Signaling in Patient-Derived T Cells. Genes (Basel) 13: pii: genes13101912. doi: 10.3390/genes13101912.

Leiding, J. W., T. P. Vogel, V. G. J. Santarlas, R. Mhaskar, M. R. Smith, A. Carisey, A. Vargas-Hernandez, M. Silva-Carmona, M. Heeg, A. Rensing-Ehl, B. Neven, J. Hadjadj, S. Hambleton, T. Ronan Leahy, K. Meesilpavikai, C. Cunningham-Rundles, C. M. Dutmer, S. O. Sharapova, M. Taskinen, I. Chua, R. Hague, C. Klemann, L. Kostyuchenko, T. Morio, A. Thatayatikom, A. Ozen, A. Scherbina, C. S. Bauer, S. E. Flanagan, E. Gambineri, L. Giovannini-Chami, J. Heimall, K. E. Sullivan, E. Allenspach, N. Romberg, S. G. Deane, B. T. Prince, M. J. Rose, J. Bohnsack, T. Mousallem, R. Jesudas, M. M. D. Santos Vilela, M. O’Sullivan, J. Pachlopnik Schmid, S. Pruhova, A. Klocperk, M. Rees, H. Su, S. Bahna, S. Baris, L. M. Bartnikas, A. Chang Berger, T. A. Briggs, S. Brothers, V. Bundy, A. Y. Chan, S. Chandrakasan, M. Christiansen, T. Cole, M. C. Cook, M. M. Desai, U. Fischer, D. A. Fulcher, S. Gallo, A. Gauthier, A. R. Gennery, J. Goncalo Marques, F. Gottrand, B. Grimbacher, E. Grunebaum, E. Haapaniemi, S. Hamalainen, K. Heiskanen, T. Heiskanen-Kosma, H. M. Hoffman, L. I. Gonzalez-Granado, A. L. Guerrerio, L. Kainulainen, A. Kumar, M. G. Lawrence, C. Levin, T. Martelius, O. Neth, P. Olbrich, A. Palma, N. C. Patel, T. Pozos, K. Preece, S. O. Lugo Reyes, M. A. Russell, Y. Schejter, C. Seroogy, J. Sinclair, E. Skevofilax, D. Suan, D. Suegeorgz, P. Szabolcs, H. Velasco, K. Warnatz, K. Walkovich, A. Worth, S. G. W. G. members, M. R. J. Seppanen, T. R. Torgerson, G. Sogkas, S. Ehl, S. G. Tangye, M. A. Cooper, J. D. Milner, and L. R. Forbes Satter. 2022. Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome. J Allergy Clin Immunol. pii: S0091-6749(22)01182-4. doi: 10.1016/j.jaci.2022.09.002.

Schutze, K., M. Gross, K. Cornils, K. Wustrau, S. Schneppenheim, H. Lenhartz, G. C. Korenke, G. Janka, S. Ledig, I. Muller, S. Ehl, and K. Lehmberg. 2022. MAP kinase activating death domain deficiency is a novel cause of impaired lymphocyte cytotoxicity. Blood Adv. pii: 486738. doi: 10.1182/bloodadvances.2022008195.

Krausz, M., A. Uhlmann, I. C. Rump, G. Ihorst, S. Goldacker, G. Sogkas, S. Posadas-Cantera, R. Schmidt, M. Feisst, L. Alsina, I. Dybedal, M. Recher, Warnatz, and B. Grimbacher. 2022. The ABACHAI clinical trial protocol: Safety and efficacy of abatacept (s.c.) in patients with CTLA-4 insufficiency or LRBA deficiency: A non controlled phase 2 clinical trial. Contemp Clin Trials Commun 30: 101008. doi: 10.1016/j.conctc.2022.101008.

Cook, J., and M. Prinz. 2022. Regulation of microglial physiology by the microbiota. Gut Microbes 14: 2125739. doi: 10.1080/19490976.2022.2125739.

Beer, J., S. Crotta, A. Breithaupt, A. Ohnemus, J. Becker, B. Sachs, L. Kern, M. Llorian, N. Ebert, F. Labroussaa, T. T. Nhu Thao, B. S. Trueeb, J. Jores, V. Thiel, M. Beer, J. Fuchs, G. Kochs, A. Wack, M. Schwemmle, and D. Schnepf. 2022. Impaired immune response drives age-dependent severity of COVID-19. J Exp Med 219: pii: 213485. doi: 10.1084/jem.20220621.

Chakraborty, S., G. Andrieux, P. Kastl, L. Adlung, S. Altamura, M. E. Boehm, L. E. Schwarzmuller, Y. Abdullah, M. C. Wagner, B. Helm, H. J. Grone, W. D. Lehmann, M. Boerries, H. Busch, M. U. Muckenthaler, M. Schilling, and U. Klingmuller. 2022. Erythropoietin-driven dynamic proteome adaptations during erythropoiesis prevent iron overload in the developing embryo. Cell Rep 40: 111360. doi: 10.1016/j.celrep.2022.111360.

Melendez, A. V., R. M. Velasco Cardenas, S. Lagies, J. Strietz, L. Siukstaite, O. S. Thomas, J. Tomisch, W. Weber, B. Kammerer, W. Romer, and S. Minguet. 2022. Novel lectin-based chimeric antigen receptors target Gb3-positive tumour cells. Cell Mol Life Sci 79: 513. doi: 10.1007/s00018-022-04524-7.

Ho, J., D. Schmidt, T. Lowinus, J. Ryoo, E. P. Dopfer, N. Gonzalo Nunez, S. Costa-Pereira, C. Toffalori, M. Punta, V. Fetsch, T. Wertheimer, M. C. Rittmann, L. M. Braun, M. Follo, C. Briere, J. M. Vinnakota, M. Langenbach, F. Koppers, K. Shoumariyeh, H. Engel, T. Ruckert, M. Marklin, S. Holzmayer, A. L. Illert, F. Magon, G. Andrieux, S. Duquesne, D. Pfeifer, J. Staniek, M. Rizzi, C. Miething, N. Kohler, J. Duyster, H. D. Menssen, M. Boerries, J. M. Buescher, N. Cabezas-Wallscheid, B. R. Blazar, P. Apostolova, L. Vago, E. L. Pearce, B. Becher, and R. Zeiser. 2022. Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation. Blood 140: 1167-1181. doi: 10.1182/blood.2022016082.

Braig, D., A. Runkel, A. E. Eisenhardt, A. Schmid, J. Zeller, T. Pauli, U. Lausch, J. Wehrle, P. Bronsert, M. Jung, J. Kiefer, M. Boerries, and S. U. Eisenhardt. 2022. Individualized Mini-Panel Sequencing of ctDNA Allows Tumor Monitoring in Complex Karyotype Sarcomas. Int J Mol Sci 23: pii: ijms231810215. doi: 10.3390/ijms231810215.

Schultz, A., M. Schnurra, A. El-Bizri, N. M. Woessner, S. Hartmann, R. Hartig, S. Minguet, B. Schraven, and L. Simeoni. 2022. A Cysteine Residue within the Kinase Domain of Zap70 Regulates Lck Activity and Proximal TCR Signaling. Cells 11. pii: cells11172723. doi: 10.3390/cells11172723.

Fliegauf, M., M. Kinnunen, S. Posadas-Cantera, N. Camacho-Ordonez, H. Abolhassani, L. Alsina, F. Atschekzei, D. J. Bogaert, S. O. Burns, J. A. Church, G. Duckers, A. F. Freeman, L. Hammarstrom, L. G. Hanitsch, T. Kerre, R. Kobbe, S. O. Sharapova, K. Siepermann, C. Speckmann, S. Steiner, N. Verma, J. E. Walter, E. Westermann-Clark, S. Goldacker, K. Warnatz, M. Varjosalo, and B. Grimbacher. 2022. Detrimental NFKB1 missense variants affecting the Rel-homology domain of p105/p50. Front Immunol 13: 965326. doi: 10.3389/fimmu.2022.965326.

Aktories, P., P. Petry, P. Glatz, G. Andrieux, A. Oschwald, H. Botterer, O. Gorka, D. Erny, M. Boerries, P. Henneke, O. Gross, M. Prinz, and K. Kierdorf. 2022. An improved organotypic cell culture system to study tissue-resident macrophages ex vivo. Cell Rep Methods 2: 100260. doi: 10.1016/j.crmeth.2022.100260.

Ramirez, N., S. Posadas-Cantera, N. Langer, A. C. G. de Oteyza, M. Proietti, B. Keller, F. Zhao, V. Gernedl, M. Pecoraro, H. Eibel, K. Warnatz, E. Ballestar, R. Geiger, C. Bossen, and B. Grimbacher. 2022. Multi-omics analysis of naive B cells of patients harboring the C104R mutation in TACI. Front Immunol 13: 938240. doi: 10.3389/fimmu.2022.938240.