Principal Investigator

Center for Medicine
Department of Rheumatology and Clinical Immunology &
Center for Chronic Immunodeficiency
Medical Center – University of Freiburg

Hugstetter Str. 55
79106 Freiburg i. Brsg.

Current position

Margarete von Wrangell Fellow, Group leader, Department of Rheumatology and Clinical Immunology, Center for Medicine, Medical Center – University of Freiburg

Academic training

2007 Specialization in Allergy and Clinical Immunology,
University of Genoa (Italy)
1993 – 1999 Study of Medicine in Genoa, Italy
2018 Habilitation in Experimental Medicine, University of Freiburg
(Mentor: Prof. Dr. Reinhard Voll)
2000 – 2004 PhD Thesis in Clinical and Experimental Immunology, University of Genoa and University of California San Diego, USA
(Supervisors: Prof. Dr. F. Indiveri – University of Genoa and
Prof. Dr. M. Zanetti - UCSD)

Postgraduate Positions

since 2014 Group leader, Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg
2011 – 2014 Postdoctorate, Center for Chronic Immunodeficiency,
Medical Center – University of Freiburg
2007 – 2011 Postdoctorate, Department of Rheumatology,
University of Freiburg
2004 – 2007 Assistant physician in Allergology and Clinical Immunology, University of Genoa, Italy
2000 – 2003 Research Fellow, Department of Medicine, University of California, San Diego, USA

Miscellaneous (Honors, Awards)

2018 Mathilde-Wagner Habilitation Prize, Gender Equality Office,
Faculty for Medicine, University of Freiburg
2015 Fellowship of the Elite program for postdocs
(Baden-Württemberg Foundation)
2014 – 2018 Speaker of the B-cell study group of the German Society of Immunology (DGfI)
2014 – 2018 Margarete von Wrangell Habilitation Fellowship (Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg)
2014 – 2016 Walter-Hitzig Fellowship (Center for Chronic Immunodeficiency)
2006 – 2007 DAAD Fellowship
2002 – 2003 A. P. Giannini Foundation: Postdoctorate Fellowship

link to all publications from M. Rizzi: Pubmed

Publications based on CRC1160 funding

Oberhardt V, Luxenburger H, Kemming J, Schulien I, Ciminski K, Giese S, Csernalabics B, Lang-Meli J, Janowska I, Staniek J, Wild K, Basho K, Marinescu MS, Fuchs J, Topfstedt F, Janda A, Sogukpinar O, Hilger H, Stete K, Emmerich F, Bengsch B, Waller CF, Rieg S, Sagar, Boettler T, Zoldan K, Kochs G, Schwemmle M, Rizzi M, Thimme R, Neumann-Haefelin C, Hofmann M. 2021. Rapid and stable mobilization of CD8+ T cells by SARS-CoV-2 mRNA vaccine. Nature.  28. doi: 10.1038/s41586-021-03841-4.

Micheau O, Rizzi M, Smulski CR. 2021. Editorial: TNFR Superfamily Oligomerization and Signaling. Front Cell Dev Biol. 9:682472.

Kury, P., J. Staniek, O. Wegehaupt, I. Janowska, M. Eckenweiler, R. Korinthenberg, N. Japaridze, M. Pendziwiat, I. Helbig, E. Verhoeyen, J. Jung, A. C. Garcia de Oteyza, M. Proietti, T. Phirtskhalaishvili, I. Rtskhiladze, P. J. Nielsen, S. Ehl, C. Speckmann, and M. Rizzi. 2021. Agammaglobulinemia with normal B-cell numbers in a patient lacking Bob1. J Allergy Clin Immunol. S0091-6749(21)00174-3. doi: 10.1016/j.jaci.2021.01.027.

Kalina, T., R. S. Abraham, Rizzi, and M. van der Burg. 2020. Editorial: Application of Cytometry in Primary Immunodeficiencies. Front Immunol 11: 463.

Troilo, A., C. Wehr, I. Janowska, N. Venhoff, J. Thiel, J. Rawluk, N. Frede, J. Staniek, R. Lorenzetti, M. T. Schleyer, G. W. Herget, L. Konstantinidis, M. Erlacher, M. Proietti, N. Camacho-Ordonez, R. E. Voll, B. Grimbacher, K. Warnatz, U. Salzer, and M. Rizzi. 2020. Nonpermissive bone marrow environment impairs early B-cell development in common variable immunodeficiency. Blood 135: 1452-1457.

Lorenzetti R, Janowska I, Smulski CR, Frede N, Henneberger N, Walter L, Schleyer MT, Hüppe JM, Staniek J, Salzer U, Venhoff A, Troilo A, Voll RE, Venhoff N, Thiel J, Rizzi M. 2019. Abatacept modulates CD80 and CD86 expression and memory formation in human B-cells. J Autoimmun. 101:145-152.

Staniek J, Lorenzetti R, Heller B, Janowska I, Schneider P, Unger S, Warnatz K, Seidl M, Venhoff N, Thiel J, Smulski CR, Rizzi M. 2019. TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes. Front Immunol. 10:951.

Rizzi, M., R. Lorenzetti, K. Fischer, J. Staniek, I. Janowska, A. Troilo, V. Strohmeier, M. Erlacher, M. Kunze, B. Bannert, D. Kyburz, E. Voll, N. Venhoff, and J. Thiel. 2017. Impact of tofacitinib treatment on human B-cells in vitro and in vivo. J Autoimmun 77: 55-66.

Janda A, Schwarz K, van der Burg M, Vach W, Ijspeert H, Lorenz MR, Elgizouli M, Pieper K, Fisch P, Hagel J, Lorenzetti R, Seidl M, Roesler J, Hauck F, Traggiai E, Speckmann C, Rensing-Ehl A, Ehl S, Eibel H, Rizzi M. 2016. Disturbed B-lymphocyte selection in autoimmune lymphoproliferative syndrome. Blood 127:2193-2202.